HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylhydrazine → 2-Methylphthalazin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylhydrazine | HCID 6061 | — |
| Reactant | alpha,alpha-Dibromomethyl-o-toluic acid | HCID 70621097 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Methylphthalazin-1-one | HCID 313378 | 75% |
Reaction Steps
A solution of 29.4 g (0.1 mole) of α,α-dibromomethyl-o-toluic acid and 14.7 g (0.32 mole) of methylhydrazine in 100 ml of ethanol was heated under reflux for 3 hours. The solvent was evaporated under reduced pressure, and the residue recrystalized from ethanol to give 12.0 g (yield: 75%) of 2-methyl-1-phthalazinone having a melting point of 111°-112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04096143 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-79b5af5e5e9a42f79021de6d70749cab |
| Source note | uspto-grants-1978_06 |