Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 22803789 | HCID 22803789 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 70616124 | HCID 70616124 | — |
Reaction Steps
A mixture of 30 mg of 3β ,19-diacetoxy-14β-hydroxy-17β-pivaloxy-5α-androstane and 3.0 ml of 0.2 N methanolic potassium hydroxide was heated at 70° C. for 16 hours under nitrogen whereupon the mixture was neutralized with 0.2 N glacial acetic acid in ethyl acetate and evaporated to dryness at reduced pressure. The residue obtained was treated with ethyl acetate and filtered through diatomaceous earth. Evaporation of the filtrate yielded 3β ,14β ,17β ,19-tetrahydroxy-5α-androstane as indicated by tlc analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04096142 |
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| Source dataset | uspto-grants-1978_06 |
|---|
| ORD ID | ord-b4d0c79b600b442aa7432348f47b48a3 |
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| Source note | uspto-grants-1978_06 |
|---|
