1,3-Benzenediamine, N1,N1,N3,N3-tetramethyl- → 2-(2-Isobutoxy-4-(dimethylamino)benzoyl)benzoic acid

Participants

Reaction Steps

In a manner similar to that of part A of Example 3 condensation of 4-(dimethylamino)phthalic anhydride (1.91 g.) and N,N,N',N'-tetramethyl-m-phenylenediamine (1.64 g.) in contact with zinc chloride (2.70 g.) and with chlorobenzene (50 ml.) as diluent afforded 2-(2,4-bis(dimethylamino)benzoyl)-4-(dimethylamino)benzoic acid (II: Y'2 = Y'4 = Z'5 = (CH3)2N, Z4 = Z'6 = Z7 = H) (m.p. 216°-222° C.) or the 5-(dimethylamino) isomer thereof.

Provenance & Evidence