反应详情

A solution of 10 g. (0.08 mole) of diethylphosphinous chloride in 100 ml. of ether was added to a solution of p-methoxyphenyllithium [prepared from 23.4 g. (0.1 mole) of p-iodoanisole in 100 ml. of ether and 62.5 ml. of 1.6 M n-butyllithium in hexane] under a nitrogen atmosphere. After 40 minutes, the reaction mixture was filtered and the solvent removed at reduced pressure. Distillation of the residual oil gave (diethyl)(p-methoxyphenyl)phosphine as a colorless liquid, b.p. 85°-90° C. at 0.5 mm.

1. filtrationthe reaction mixture was filtered
2. customthe solvent removed at reduced pressure
3. distillationDistillation of the residual oil