Acetic Anhydride → HCID 20323729, compound

HRID 839615Notes

Reaction equation

HRID 839615 reaction equation
[CH2:1]([O:3][CH:4]([O:13][CH2:14][CH3:15])[CH2:5][NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=1)[CH3:2].[C:16](OC(=O)C)(=[O:18])[CH3:17]>N1C=CC=CC=1>[CH2:1]([O:3][CH:4]([O:13][CH2:14][CH3:15])[CH2:5][N:6]([C:16](=[O:18])[CH3:17])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=1)[CH3:2]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 25136988HCID 25136988, compound

Product 1

HCID 20323729HCID 20323729, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
80 °C

Procedure

A solution of 2-pyridylaminoacetaldehyde diethyl acetal (8.0 g.) in a mixture of acetic anhydride (30 ml.) and pyridine (30 ml.) was stirred for 4 hours at 80° C and allowed to stand for 12 hours at ambient temperature. The reaction mixture was post-treated according to a similar manner to that of Example 5 (a) (2) to give oil of N-acetyl-N-(2-pyridyl)aminoacetaldehyde diethyl acetal (6 g.).

Workup

  1. waitto stand for 12 hours at ambient temperature
  2. additionThe reaction mixture was post-treated

Sources & evidence

ORD record
ord-33998cd168b14d8a896e2f6a637a45c3
Source dataset
uspto-grants-1978_06
Patent number
US04096263

Reaction notes

Loading…