2,3-Dichloro-4-(2-phenylacryloyl)anisole → 2-Phenyl-5-methoxy-6,7-dichloro-1-indanone

Participants

Reaction Steps

2,3-Dichloro-4-(2-phenylacryloyl)anisole (7.4 g., 0.024 mole) is added portionwise to cold, concentrated sulfuric acid (150 ml.) with stirring. The reaction mixture is stirred in an ice bath for 2 hours, then added dropwise to ice-water to precipitate 3.91 g. of 2-phenyl-5-methoxy-6,7-dichloro-1-indanone which melts at 193°-195° C. upon crystallization from benzene:cyclohexane, 1:2.

Provenance & Evidence