HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 839700Generated: October 30, 2026
Water → Tert-butyl(1-oxo-2-methyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetate
https://huagongshe.com/reaction/839700
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | 6,7-Dichloro-5-hydroxy-2-methyl-2-phenylindan-1-one | HCID 93690 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Tert-butyl(1-oxo-2-methyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetate | HCID 20384375 | — |
Reaction Steps
A mixture of 2-methyl-2-phenyl-5-hydroxy-6,7-dichloro-1-indanone (9.2 g., 0.03 mole), potassium carbonate (8.29 g., 0.06 mole) and tert-butyl bromoacetate (6.44 g., 0.033 mole) in dimethylformamide (30 ml.) is stirred at 25° C. for two hours. The reaction mixture is poured into cold water (150 ml.) and the tert-butyl (1-oxo-2-methyl-2-phenyl-6,7-dichloro-5-indanyloxy)acetate which separates is filtered, rinsed with water and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04096267 |
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| Source dataset | uspto-grants-1978_06 |
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| ORD ID | ord-93bfc26bcb3c485badd982c20c922305 |
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| Source note | uspto-grants-1978_06 |
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