Hydrochloric Acid → HCID 20321812, compound

Participants

Reaction Steps

A solution of 91.8 grams of 2,6-bis(1,1-dimethylbutyl)-4-(α-hydroxyethyl)phenol in 400 milliliters of hexane was stirred vigorously with 400 milliliters of concentrated HCl for 1 hour. The hexane layer was separated and the hexane was removed by distillation under aspirator vacuum. The residual 2,6-bis(1,1-dimethylbutyl)-4-(α-chloroethyl) phenol was dissolved in 150 milliliters of pyridine and the solution was heated under reflux for 1 hour. Pyridine was removed by distillation under aspirator vacuum. The residue was washed with water, then dried in a vacuum oven. The product, a viscous yellow liquid, weighed 26 grams.

Provenance & Evidence