HCID 86735796, compound → HCID 86735794, compound
Reaction equation
[ClH:1].Cl.[F:3][C:4]([F:22])([F:21])C1C=CC(N2C3C(=CC=CC=3)CCC2)=CC=1.Cl.Cl.[CH3:25][C:26]1([CH3:49])[CH2:35][CH:34]([C:36]2[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][CH:37]=2)[CH:33]2[C:28](=[CH:29][C:30]([O:43][CH2:44][CH2:45][N:46]([CH3:48])[CH3:47])=[CH:31][CH2:32]2)[NH:27]1>>[ClH:42].[ClH:1].[CH3:25][C:26]1([CH3:49])[CH2:35][CH:34]([C:36]2[CH:41]=[CH:40][CH:39]=[C:38]([C:4]([F:22])([F:21])[F:3])[CH:37]=2)[CH:33]2[C:28](=[CH:29][C:30]([O:43][CH2:44][CH2:45][N:46]([CH3:48])[CH3:47])=[CH:31][CH2:32]2)[NH:27]1Participants
3
Procedure
2,2-dimethyl-7-dimethylaminoethoxy-4-(4-trifluoromethylphenyl-tetrahydroquinoline dihydrochloride m.p. 141°-8°; and 2,2-dimethyl-7-dimethylaminoethoxy-4-(4-chlorophenyl)tetrahydroquinoline dihydrochloride m.p. 139°-143°.
Sources & evidence
- ORD record
- ord-d16fc42b90d54113abbce32c97b17cb4
- Source dataset
- uspto-grants-1978_06
- Patent number
- US04097480
Reaction notes
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