Potassium Hydroxide → HCID 20321996, compound

Participants

Reaction Steps

A mixture of 2-isopropylpyrazolo[1,5-a]pyridine and β-ethoxy-α-methylpropionic chloride was dissolved in carbon disulfide. Aluminum chloride was added at 0° to the resulting solution. The reaction mixture was stirred for 3 hr, and poured into water. The solution was made basic with potassium hydroxide solution and extracted with chloroform. The chloroform solution was washed with water, dried over sodium sulfate and concentrated. The residue was distilled, bp 171°-173° (4 mmHg). Yield 32%.

Provenance & Evidence