反应详情

温度

-15 °C

25.5 g of chromic oxide were added in small fractions at 15° to 20° C to a solution of 41 ml of pyridine in 400ml of anhydrous methylene chloride and the mixture was stirred for 15 minutes. The mixture was cooled to -15° C and a solution of 4.3 g of the product of Step A in 10 ml of methylene chloride was added thereto. After 11/2 hours, 50 g of celite and 100 ml of ether were added thereto and the mixture was filtered. The filtrate was washed with ether and the filtrate was evaporated to dryness at 30° C to obtain methyl (5RS) 2-methoxy-5-formyl-1-cyclopentenecarboxylate.

1. filtrationthe mixture was filtered
2. washThe filtrate was washed with ether
3. customthe filtrate was evaporated to dryness at 30° C