4-Amino-5-chloro-2-methoxybenzoic acid → HCID 53776689, compound

HRID 839826Notes

Reaction equation

HRID 839826 reaction equation
[NH2:1][C:2]1[C:10]([Cl:11])=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([O:12][CH3:13])[CH:3]=1.[NH2:14][CH2:15][CH:16]1[CH2:20][CH2:19][CH:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[N:17]1[CH2:27][CH3:28]>>[CH2:27]([N:17]1[CH:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH2:19][CH2:20][CH:16]1[CH2:15][NH:14][C:6](=[O:8])[C:5]1[CH:9]=[C:10]([Cl:11])[C:2]([NH2:1])=[CH:3][C:4]=1[O:12][CH3:13])[CH3:28]

Participants

3

Reactant 2

HCID 816264-Amino-5-chloro-2-methoxybenzoic acidHCID 12861926HCID 12861926, compound

Product 1

HCID 53776689HCID 53776689, compound

Procedure

By following general method B using 1.01 g. of 4-amino-5-chloro-2-methoxybenzoic acid and 1.0 g. of 2-aminomethyl-1-ethyl-5-phenylpyrrolidine, 1.8 g. of N-(1-ethyl-5-phenyl-2-pyrrolidinylmethyl)-4-amino-5-chloro-2-methoxybenzamide was obtained.

Sources & evidence

ORD record
ord-9c163c445b354d5f95b1231d1a6eae5d
Source dataset
uspto-grants-1978_06
Patent number
US04097487

Reaction notes

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