1-Benzyl-3-aminopyrrolidine → HCID 12861944, compound

HRID 839828Notes

Reaction equation

HRID 839828 reaction equation
[Cl:1][C:2]1[C:3]([N:13]([CH3:15])[CH3:14])=[CH:4][C:5]([O:11][CH3:12])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[NH2:16][CH:17]1[CH2:21][CH2:20][N:19]([CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH2:18]1>>[CH2:22]([N:19]1[CH2:20][CH2:21][CH:17]([NH:16][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([Cl:1])[C:3]([N:13]([CH3:15])[CH3:14])=[CH:4][C:5]=2[O:11][CH3:12])[CH2:18]1)[C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 27566131-Benzyl-3-aminopyrrolidineHCID 110752025-Chloro-4-dimethylamino-2-methoxybenzoic acid

Product 1

HCID 12861944HCID 12861944, compound

Procedure

By following general method A using 0.85 g. of 5-chloro-4-dimethylamino-2-methoxybenzoic acid and 0.65 g. of 3-amino-1-benzylpyrrolidine, 0.8 g. of N-(1-benzyl-3-pyrrolidinyl)-5-chloro-4-dimethylamino-2-methoxybenzamide was obtained.

Sources & evidence

ORD record
ord-ac641d8623db464aacb6d35384b60aa9
Source dataset
uspto-grants-1978_06
Patent number
US04097487

Reaction notes

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