1-Benzyl-3-aminopyrrolidine → HCID 20344794, compound

HRID 839829Notes

Reaction equation

HRID 839829 reaction equation
[Cl:1][C:2]1[C:3]([NH:13][CH3:14])=[CH:4][C:5]([O:11][CH3:12])=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[NH2:15][CH:16]1[CH2:20][CH2:19][N:18]([CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:17]1>>[ClH:1].[CH2:21]([N:18]1[CH2:19][CH2:20][CH:16]([NH:15][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([Cl:1])[C:3]([NH:13][CH3:14])=[CH:4][C:5]=2[O:11][CH3:12])[CH2:17]1)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 27566131-Benzyl-3-aminopyrrolidineHCID 116942165-Chloro-2-methoxy-4-(methylamino)benzoic acid

Product 1

HCID 20344794HCID 20344794, compound

Procedure

By following general method C using 1.7 g. of 5-chloro-2-methoxy-4-methylaminobenzoic acid and 1.4 g. of 3-amino-1-benzylpyrrolidine, 2.1 g. of N-(1-benzyl-3-pyrrolidinyl)-5-chloro-2-methoxy-4-methylaminobenzamide hydrochloride was obtained.

Sources & evidence

ORD record
ord-85ba067af2cb4df89858f5e2ed8acbb2
Source dataset
uspto-grants-1978_06
Patent number
US04097487

Reaction notes

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