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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 839834Generated: October 26, 2026

Sodium Hydroxide → 2-Methyl-6-phenoxy-hexanoic acid

https://huagongshe.com/reaction/839834

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantMethyl-(4-phenoxybutyl)-malonic acid diethyl esterHCID 53773953—
SolventEthanolHCID 702—
Product2-Methyl-6-phenoxy-hexanoic acidHCID 20322135—

Reaction Steps

242 g of methyl-(4-phenoxybutyl)-malonic acid diethyl ester, 1000 ml of a 20% sodium hydroxide solution and 100 ml of ethanol were refluxed for 12 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04097496
Source datasetuspto-grants-1978_06
ORD IDord-4353ae3132914cbd9a14b81cbe1f47de
Source noteuspto-grants-1978_06