反应详情

70 g (345 mmols) of 3-(2-Chloromethylphenyl)-propyl chloride (JACS 75, 2053 (1953)) and 50 g (0.61 mmol) of sodium acetate were heated to the boiling point while stirring in 250 ml of glacial acetic acid. It resulted from the thin layer chromatography that the reaction was finished after 41/2 hours. After cooling about 700 ml of water were added and the product was extracted with benzene. The organic phase was washed with water, dried and distilled off after evaporation of the solvent.

1. customIt resulted from the thin layer chromatography that the reaction
2. custom2 hours
3. additionwere added
4. extractionthe product was extracted with benzene
5. washThe organic phase was washed with water
6. customdried
7. distillationdistilled off
8. customafter evaporation of the solvent