HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → HCID 54006150, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 1,1'-(Diazomethylene)bis(benzene) | HCID 61230 | — |
| Reactant | Glycine, 4-methylbenzenesulfonate | HCID 6452034 | — |
| Reactant | HCID 66916607 | HCID 66916607 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 54006150 | HCID 54006150 | — |
Reaction Steps
A suspension of 20 g. of glycine diphenylmethyl ester hydrochloride (prepared by reacting glycine tosylate and diphenyldiazomethane in dioxane followed by conversion to the hydrochloride salt) in 300 ml. of toluene is heated to boiling with stirring. At the boiling temperature, a strong stream of phosgene is passed through the suspension for three hours. The isocyanatoacetic acid, diphenylmethyl ester is then isolated by distillation; b.p.0.01 160°-170°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04097670 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-8aa09da9d0644d93ad5c8e4973745176 |
| Source note | uspto-grants-1978_06 |