HRID839973

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24386

Thionyl chloride

Cl2OS

结构：CCCCCC(CCCC(CCCCCCC(=O)OCC)C(=O)O)OC(C)=O

HCID21317594

未命名化合物

PRODUCTS

生成物

结构：CCCCCC(CCCC(CCCCCCC(=O)OCC)C(=O)Cl)OC(C)=O

HCID20322197

Ethyl 12-(acetyloxy)-8-(chlorocarbonyl)heptadecanoate

C22H39ClO5

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID241

Benzene

C6H6

PROCEDURE

实验过程

A solution of ethyl 8-carboxy-12-acetoxyheptadecanoate (12.0 g., 0.03 mole) and thionyl chloride (7.2 g., 0.06 mole) in benzene (50 ml.) is refluxed for 2.5 hours. Volatile materials are removed by using a rotary evaporator in vacuo. The residual product, ethyl 8-chlorocarbonyl-12-acetoxyheptadecanoate, is a viscous liquid weighing 12.5 g. (100%), ir (neat) 7990 cm-1 (acid chloride C=O), 1730 cm-1 (ester C=O). This material is used directly in the next step.

WORKUP

后处理

customVolatile materials are removed
customa rotary evaporator in vacuo