6-Methoxy-1,2,3,4-tetrahydronaphthalen-2-one → 6-Methoxynaphthyl-alpha-methylacetic acid

Participants

Reaction Steps

Thus, for example, by reacting 6-methoxy-2-tetralone with the triphenylphosphorane derived from ethyl 2-halopropionate, 2,2-(1'-carbethoxyeth-1', 1'-ylidene)-6-methoxytetralin is prepared. Dehydrogenation thereof provides ethyl 6-methoxynaphthyl-α-methylacetate which upon hydrolysis affords 6-methoxynaphthyl-α-methylacetic acid.

Provenance & Evidence