(2S)-2-Methyloxirane → HCID 69835372, compound

Participants

Reaction Steps

(S)-1-(1H-Pyrrolo[2,3-f]quinolin-1-yl)-2-propanol was prepared according to the method described in Example 1 using 1H-pyrrolo[2,3-f]quinoline and (S)-propylene oxide to produce 0.36 g (17% yield) of the product as a pale yellow oil: IRνmax (Nujol)/cm−1 3106, 1361, 1117, 826, 805 and 731; NMR δH (400 MHz, CDCl3) 1.36 (3H, d, J 6.0 Hz), 2.75 (1H, br), 4.44 (2H, m), 4.56 (1H, m), 6.63 (1H, d, J 3.0 Hz), 7.19 (1H, d, J 3.0 Hz), 7.30 (1H, dd, J 8.5 and 4.0 Hz), 7.70 (1H, d, J 8.5 Hz), 7.86 (1H, d, J 9.0 Hz), 8.53 (1H, d, J 9.0 Hz) and 8.66 (1H, d, J 4.0 Hz).

Provenance & Evidence