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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 840313Generated: October 29, 2026

3-Bromo-1,1,1-Trifluoro-2-Propanol → n-Butyl 6-[N-(5-bromo-2-(2-hydroxy-3,3,3-trifluoropropoxy)benzyl)-N-ethylamino]pyridazine-3-carboxylate

https://huagongshe.com/reaction/840313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-1,1,1-Trifluoro-2-PropanolHCID 220632—
Reactantbutyl 6-[N-(5-bromo-2-hydroxybenzyl)-N-ethylamino]pyridazine-3-carboxylateHCID 22622486—
Productn-Butyl 6-[N-(5-bromo-2-(2-hydroxy-3,3,3-trifluoropropoxy)benzyl)-N-ethylamino]pyridazine-3-carboxylateHCID 22622518—

Reaction Steps

The title compound was prepared by reacting 3-bromo-1,1,1-trifluoropropan-2-ol and butyl 6-[N-(5-bromo-2-hydroxybenzyl)-N-ethylamino]pyridazine-3-carboxylate using a similar method to that of reference example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06365603B1
Source datasetuspto-grants-2002_04
ORD IDord-dd8324eec18e4220bcdb3dc9c18efe67
Source noteuspto-grants-2002_04