HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloropyridazine-3-carbonitrile → 6-[N-(5-Bromo-2-hydroxybenzyl)-N-ethylamino]-3-cyanopyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloropyridazine-3-carbonitrile | HCID 13382871 | — |
| Reactant | N-ethyl-5-bromo-2-hydroxybenzylamine hydrochloride | HCID 22622504 | — |
| Product | 6-[N-(5-Bromo-2-hydroxybenzyl)-N-ethylamino]-3-cyanopyridazine | HCID 22622514 | 50% |
Reaction Steps
The title compound was prepared by reacting N-ethyl-5-bromo-2-hydroxybenzylamine hydrochloride and 3-chloro-6-cyanopyridazine using a similar method to that of reference example 18 except eluting with 2% diethyl ether/dichloromethane in the chromatography (yield 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06365603B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-01def716fe8e4d1dbf543ef9f28ef803 |
| Source note | uspto-grants-2002_04 |