Acetic Acid → HCID 91486166, compound

Participants

Reaction Steps

A mixture of 0.52 g of 3-(5-amino-2-chlorophenyl)-2-chloroacrylate, 0.36 g of phthalic anhydride, and 4 ml of acetic acid was heated under reflux for 2 hours under stirring. After cooling, water was added to the reaction mixture, and the precipitated solid was collected by filtration. The solid thus obtained was washed with water, dried, and purified by silica gel column chromatography (chloroform-hexane=3:1) to yield 0.71 g of the title compound (No. 18 of Table 2).

Provenance & Evidence