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HRID840421

反应详情

EQUATION

反应方程式

HRID 840421 的结构方程式

REACTANTS

反应物

2
结构：O=C(Cl)c1cc([N+](=O)[O-])cc2ccccc12
HCID10657422

3-nitro-1-naphthoyl chloride

C11H6ClNO3

结构：CNC[C@@H](CCO)c1ccc(Cl)c(Cl)c1
HCID20794252

(γS)-3,4-Dichloro-γ-[(methylamino)methyl]benzenepropanol

C11H15Cl2NO

PRODUCTS

生成物

1
结构：CN(C[C@@H](CCO)c1ccc(Cl)c(Cl)c1)C(=O)c1cc([N+](=O)[O-])cc2ccccc12
HCID57320371

未命名化合物

PROCEDURE

实验过程

By the method of Example 3f, 3-nitro-1-naphthoyl chloride was reacted with (S)-2-(3,4-dichlorophenyl)-4-hydroxybutyl-N-methylamine to give N-[(S)-2-(3,4-dichlorophenyl)-4-hydroxybutyl]-N-methyl-3-nitro-1-naphthamide. This was reacted by the method of Example 3g to give the title compound: 1H NMR (300 MHz, CDCl3) δ 9.65 (s), 9.44 (s), 9.07-9.02 (m), 8.38-6.04 (m), 4.44-1.18 (m); MS APCI, m/z=445 (M+).