反应详情

500 mg (1.38 mmol) of 4-(3-hydroxy-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propynyl]benzoic acid, 50 ml of dichloromethane and 2.4 g (27.6 mmol) of manganese oxide were introduced into a round-bottomed flask which was placed in an ultrasonic bath for 4 hours. The reaction mixture was filtered, the filtrate was evaporated and the residue was purified by simple filtration through silica in ethyl ether. 90 mg (18%) of the expected compound, with a melting point of 208°-209° C., were recovered.

1. filtrationThe reaction mixture was filtered
2. customthe filtrate was evaporated
3. filtrationthe residue was purified by simple filtration through silica in ethyl ether
4. custom90 mg (18%) of the expected compound, with a melting point of 208°-209° C., were recovered