HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilylacetylene → Methyl 2-hydroxy-4-trimethylsilylethynylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilylacetylene | HCID 66111 | — |
| Reactant | Methyl 4-iodosalicylate | HCID 11380407 | — |
| Product | Methyl 2-hydroxy-4-trimethylsilylethynylbenzoate | HCID 22641103 | 85.5% |
Reaction Steps
Following the basic procedure of Example 1(a), by reacting 34 g (122 mmol) of methyl 2-hydroxy-4-iodobenzoate with 34 ml (244 mmol) of trimethylsilylacetylene, 25.9 g (85%) of the expected compound were obtained in the form of a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06368608B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-48eec108af0e4d80905bc3b4776d2d48 |
| Source note | uspto-grants-2002_04 |