反应详情

A mixture of indoline (D4, 2.84 g, 14 mmol) and acetic anhydride (1.32 ml, 14 mmol) in dry dichloromethane (50 ml) was stirred at room temperature for 3 h, then evaporated. The residue was treated cautiously with saturated sodium bicarbonate solution, then the solid product was filtered off, washed with water and dried to give the title compound (3.28 g, 96%), m.p. 244-7° C.

1. customevaporated
2. additionThe residue was treated cautiously with saturated sodium bicarbonate solution
3. filtrationthe solid product was filtered off
4. washwashed with water
5. customdried