Water → HCID 22619820, compound

HRID 840561Notes

Reaction equation

HRID 840561 reaction equation
[CH3:1][C:2]1([CH3:14])[NH:11][C:10]2[C:5](=[CH:6][C:7]([CH3:12])=[CH:8][CH:9]=2)[NH:4][C:3]1=[O:13].Cl[C:16]([O:18][C:19]([CH3:21])=[CH2:20])=[O:17].O>N1C=CC=CC=1>[C:19]([O:18][C:16]([N:11]1[C:10]2[C:5](=[CH:6][C:7]([CH3:12])=[CH:8][CH:9]=2)[NH:4][C:3](=[O:13])[C:2]1([CH3:14])[CH3:1])=[O:17])([CH3:21])=[CH2:20]

Participants

5

Reactant 3

HCID 962WaterHCID 93846Isopropenyl chloroformateHCID 226197853,3,7-Trimethyl-3,4-dihydroquinoxalin-2(1H)-one

Product 1

HCID 22619820HCID 22619820, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

3,3,7-Trimethyl-3,4-dihydroquinoxalin-2(1H)-one (0.4 g, 2.1 mmol) were dissolved in 10 ml of anhydrous pyridine, and the stirred solution was treated at room temperature with 0.24 ml (2.2 mmol) of isopropenyl chloroformate. The mixture was stirred for 6 hours at room temperature and treated with water, the precipitate which formed was filtered off with suction, washed with water and dried. This gave 0.4 g (69%) of colorless crystals of melting point 185° C.

Workup

  1. customthe precipitate which formed
  2. filtrationwas filtered off with suction
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-38d40e233bf949469a8fc27c110bf65a
Source dataset
uspto-grants-2002_04
Patent number
US06369057B1

Reaction notes

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