HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-2-thiophenecarboxaldehyde → Methyl 1,2,3,4-tetrahydro-1-(5-methyl-2-thienyl)-9h-pyrido [3,4-b]indole-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-2-thiophenecarboxaldehyde | HCID 61663 | — |
| Reactant | L-Tryptophan, methyl ester | HCID 77980 | — |
| Product | Methyl 1,2,3,4-tetrahydro-1-(5-methyl-2-thienyl)-9h-pyrido [3,4-b]indole-3-carboxylate | HCID 3879449 | — |
Reaction Steps
The same method but starting from racemic tryptophan methyl ester and 5-methyl-2-thiophenecarboxaldehyde gave the cis and trans isomers of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06369059B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-3b22efda8a8a4ffaa4648109303e08bb |
| Source note | uspto-grants-2002_04 |