Methyl 2-hydroxy-3-phenylpropanoate → HCID 10649445, compound

HRID 840626Notes

Reaction equation

HRID 840626 reaction equation
[Br:1][C:2]1[O:3][C:4]2[CH:23]=[CH:22][CH:21]=[CH:20][C:5]=2[C:6]=1[C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=2)=[CH:9][CH:8]=1.C[O:25][C:26](=[O:36])[CH:27]([CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)O>>[Br:1][C:2]1[O:3][C:4]2[CH:23]=[CH:22][CH:21]=[CH:20][C:5]=2[C:6]=1[C:7]1[CH:8]=[CH:9][C:10]([C:13]2[CH:18]=[CH:17][C:16]([O:19][CH:27]([CH2:29][C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)[C:26]([OH:36])=[O:25])=[CH:15][CH:14]=2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 518800Methyl 2-hydroxy-3-phenylpropanoateHCID 10666503HCID 10666503, compound

Product 1

HCID 10649445HCID 10649445, compound

Procedure

The title compound was prepared from 4′-(2-bromo-benzofuran-3-yl)-biphenyl-4-ol and 3-phenyllactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h, and was obtained as a white solid, mp 148-149° C.; MS m/e 512 (M+);

Workup

  1. customwas obtained as a white solid, mp 148-149° C.

Sources & evidence

ORD record
ord-e93de13813a040978db5852ee32a1d12
Source dataset
uspto-grants-2002_04
Patent number
US06369072B2

Reaction notes

Loading…