Methyl 2-hydroxy-3-phenylpropanoate → HCID 10648773, compound

HRID 840627Notes

Reaction equation

HRID 840627 reaction equation
[CH2:1]([C:5]1[O:6][C:7]2[CH:26]=[CH:25][CH:24]=[CH:23][C:8]=2[C:9]=1[C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH3:4].C[O:28][C:29](=[O:39])[CH:30]([CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)O>>[CH2:1]([C:5]1[O:6][C:7]2[CH:26]=[CH:25][CH:24]=[CH:23][C:8]=2[C:9]=1[C:10]1[CH:11]=[CH:12][C:13]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH:30]([CH2:32][C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)[C:29]([OH:39])=[O:28])=[CH:18][CH:17]=2)=[CH:14][CH:15]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 518800Methyl 2-hydroxy-3-phenylpropanoateHCID 10854796HCID 10854796, compound

Product 1

HCID 10648773HCID 10648773, compound

Procedure

The title compound was prepared from 4′-(2-butyl-benzofuran-3-yl)-biphenyl-4-ol, and 3-phenyllactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h, and was obtained as a white solid, mp 169-170° C.; MS m/e 491 (M+H)+;

Workup

  1. customwas obtained as a white solid, mp 169-170° C.

Sources & evidence

ORD record
ord-0f620f57fc3d4a5294a9c4e4275b1c64
Source dataset
uspto-grants-2002_04
Patent number
US06369072B2

Reaction notes

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