Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 840632Generated: October 30, 2026

methyl (S)-lactate → (2R)-2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-propionic acid

https://huagongshe.com/reaction/840632

Reaction equation

Participants

RoleNameHCIDCharge
Reactantmethyl (S)-lactateHCID 94386—
Reactant4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-olHCID 10547545—
Product(2R)-2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-propionic acidHCID 10765880—

Reaction Steps

The title compound was prepared from 4′-(2-benzyl-benzofuran-3-yl)-biphenyl-4-ol, and (S)-(+)- lactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h, and was obtained as a white solid, mp 112-114° C.; MS m/e 448 (M+);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06369072B2
Source datasetuspto-grants-2002_04
ORD IDord-1189b20f48e64bc6a3a14a1698e3c79b
Source noteuspto-grants-2002_04