HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl (S)-lactate → (2R)-2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl (S)-lactate | HCID 94386 | — |
| Reactant | 4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-ol | HCID 10547545 | — |
| Product | (2R)-2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-propionic acid | HCID 10765880 | — |
Reaction Steps
The title compound was prepared from 4′-(2-benzyl-benzofuran-3-yl)-biphenyl-4-ol, and (S)-(+)- lactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h, and was obtained as a white solid, mp 112-114° C.; MS m/e 448 (M+);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06369072B2 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-1189b20f48e64bc6a3a14a1698e3c79b |
| Source note | uspto-grants-2002_04 |