4-Bromotoluene → 2-Bromo-5-methylbenzene-1-sulfonyl chloride

Participants

Reaction Conditions

Reaction Steps

40 g of 4-bromotoluene are slowly introduced into 250 ml of chlorosulfonic acid at −10° C. with stirring. The mixture is stirred at this temperature for 30 minutes, allowed to warm to 0° C. and poured on to excess ice. The product is filtered off with suction and washed with a little water. It is dried over P4O10 in vacuo and 63 g of a colorless solid are obtained, which is directly reacted further.

Provenance & Evidence