反应详情

49.6 g of 2-bromo-5-methylbenzenesulfinic acid are dissolved in 400 ml of methanol and treated with an equimolar amount of NaOH in 50 ml of water. The mixture is stirred at RT for 3 hours, the solution is filtered off and the solvents are then removed in vacuo. Finally, residues of water are removed azeotropically using 50 ml of toluene. The solid residue is dried in vacuo over P4O10 and 54.0 g of product are obtained, mp 288-290° C. (with decomposition).

1. filtrationthe solution is filtered off
2. customthe solvents are then removed in vacuo
3. customFinally, residues of water are removed azeotropically
4. dry with materialThe solid residue is dried in vacuo over P4O10 and 54.0 g of product
5. customare obtained