HCID 10207799, compound → HCID 10116312, compound

Participants

Reaction Steps

To a solution of the alcohol of example 4 (0.7 g, 1.5 mmol) in dichloromethane was added manganese dioxide (1.26 g, 14.5 mmol) and the slurry was stirred overnight at room temperature. The reaction mixture was then filtered through a pad of celite and the volatils were evaporated under reduced pressure to give a residue which was purified by flash chromatography (70% CH2Cl2/30% AcOEt) to provide the title compound (0.33 g). 1H nmr (400 MHz, acetone-d6) δ ppm 8.78 (1H, d, J=2.1 Hz), 8.48 (1H, d, J =2.2 Hz), 7.96 (1H, t, J=2.1 Hz), 7.60 (1H, d, J=5.1 Hz), 7.35-7.05 (9H, m), 4.94 (2H, s).

Provenance & Evidence