HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzyl chloride → 2-Fluoro-4-(4-fluoro-benzyloxy)-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzyl chloride | HCID 9602 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Fluoro-4-nitrophenol | HCID 520948 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Fluoro-4-(4-fluoro-benzyloxy)-nitrobenzene | HCID 22137940 | — |
Reaction Steps
The starting compound 2-fluoro-4-(4-fluorobenzyloxy)nitrobenzene (m.p.: 99° C.) was prepared by alkylation of 3-fluoro-4-nitrophenol with 4-fluorobenzyl chloride in DMF in the presence of potassium carbonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06369088B2 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-2266495fd52a49a397d0e22da6835480 |
| Source note | uspto-grants-2002_04 |