Cyclohexanecarbonyl chloride → HCID 178521898, compound

HRID 840741Notes

Reaction equation

HRID 840741 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:9][C:10]3[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.[CH:18]1([C:24](Cl)=[O:25])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([C:24]([NH:1][C:2]2[CH:3]=[CH:4][C:5]([C:8]3[NH:9][C:10]4[CH:16]=[CH:15][C:14]([NH:17][C:24]([CH:18]5[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]5)=[O:25])=[CH:13][C:11]=4[N:12]=3)=[CH:6][CH:7]=2)=[O:25])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 75938Cyclohexanecarbonyl chlorideHCID 178507432HCID 178507432, compound

Product 1

HCID 178521898HCID 178521898, compound

Procedure

2-(N-Cyclohexylcarbanoyl-4′-aminophenyl)-6-(cyclohexylcarbanoylamino)-benzimidazole was prepared by Method A from 2-(4-aminophenyl)-6-aminobenzimidazole (0.195 g, 0.87 mmole) and cyclohexylcarbonyl chloride (0.291 ml, 0.319 g, 2.175 mmole). The resulting solid (76.7 mg) was purified by preparative HPLC.

Workup

  1. customThe resulting solid (76.7 mg) was purified by preparative HPLC

Sources & evidence

ORD record
ord-636f4961eeb44a5f9278115991c9dc3d
Source dataset
uspto-grants-2002_04
Patent number
US06369091B1

Reaction notes

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