4-Hydrazinylbenzenesulfonamide hydrochloride → HCID 178514740, compound

HRID 840832Notes

Reaction equation

HRID 840832 reaction equation
N1C=CC(C2C=C(C=CC=2)N)=N1.[NH:13]1[CH:17]=[CH:16][C:15]([C:18]2[CH:26]=[CH:25][CH:24]=[C:23]3[C:19]=2[C:20](=[O:28])[C:21](=[O:27])[NH:22]3)=[N:14]1.[CH:29]1[C:34]([NH:35][NH2:36])=[CH:33][CH:32]=[C:31]([S:37]([NH2:40])(=[O:39])=[O:38])[CH:30]=1.Cl>>[NH:13]1[CH:17]=[CH:16][C:15]([C:18]2[CH:26]=[CH:25][CH:24]=[C:23]3[C:19]=2[C:20](=[O:28])[C:21](=[O:27])[NH:22]3)=[N:14]1.[O:27]=[C:21]1[C:20](=[N:36][NH:35][C:34]2[CH:33]=[CH:32][C:31]([S:37]([NH2:40])(=[O:38])=[O:39])=[CH:30][CH:29]=2)[C:19]2[C:23](=[CH:24][CH:25]=[CH:26][C:18]=2[C:15]2[CH:16]=[CH:17][NH:13][N:14]=2)[NH:22]1

Participants

5

Reactant 3

HCID 27945674-Hydrazinylbenzenesulfonamide hydrochlorideHCID 178507526HCID 178507526, compoundHCID 178517148HCID 178517148, compound

Product 2

HCID 178514740HCID 178514740, compoundHCID 178517148HCID 178517148, compound

Procedure

4-(1H-Pyrazol-3-yl)-1H-indole-2,3-dione was prepared from 3-(1H-pyrazol-3-yl)aniline according to Procedure A. The title compound was prepared from 4-(1H-pyrazol-3-yl)isatin and 4-sulfonamidophenylhydrazine hydrochloride according to Procedure G: 1H NMR (DMSO-d6): δ6.72 (s,1H), 7.22 (s, 2H), 7.39 (s, 1H), 7.48-7.60 (m, 4H), 7.76 (d, J=8.7 Hz, 2H), 7.77 (s, 1H), 11.11 (s, 1H), 12.93 (s, 1H); ESI−MS: m/z 381 (M−H)−.

Sources & evidence

ORD record
ord-193269ca7a2748bdb5d56f91d7ae6507
Source dataset
uspto-grants-2002_04
Patent number
US06369086B1

Reaction notes

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