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HRID840855

反应详情

EQUATION

反应方程式

HRID 840855 的结构方程式

REACTANTS

反应物

2
结构：Cl.NNc1ccc(S(N)(=O)=O)cc1
HCID2794567

4-Hydrazinylbenzene-1-sulfonamide--hydrogen chloride (1/1)

C6H10ClN3O2S

结构：CCc1ccc2c(c1)NC(=O)C2=O
HCID13827083

6-Ethyl-1H-indole-2,3-dione

C10H9NO2

PRODUCTS

生成物

1
结构：CCc1ccc2c(c1)NC(=O)C2=NNc1ccc(S(N)(=O)=O)cc1
HCID178435488

未命名化合物

收率 79%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

The title compound was prepared from 6-ethyl-1H-indole-2,3-dione (Krantz and Young, 1989, U.S. Pat. No. 4,873,232) and 4-sulfonamidophenylhydrazine hydrochloride according to Procedure G in 79% yield: 1H NMR (DMSO-d6): δ1.16 (t, J=7.5 Hz, 3H), 2.60 (q, J=7.5 Hz, 2H), 6.74 (s, 1H), 6.89 (d, J=7.5 Hz, 1H), 7.22 (s, 2H), 7.46 (d, J=7.5 Hz, 1H), 7.50 (d, J=8.7 Hz, 1H), 7.75 (d, J=8.7 Hz, 2H), 11.02 (s, 1H), 12.70 (s, 1H); APCI−MS m/z 343 (M−H)−. Anal. Calcd for C16H16N4O3S.0.32 H2O: C, 54.88, H, 4.79; N, 16.00; S, 9.16. Found C, 54.81, H, 4.59; N, 16.06; S, 9.04.