phenyl 4-aminobenzenesulfonate → HCID 178517094, compound

HRID 840856Notes

Reaction equation

HRID 840856 reaction equation
O[CH:2]=[C:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5][C:4]1=[O:12].[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([O:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[C:24]1([O:23][S:20]([C:17]2[CH:16]=[CH:15][C:14]([NH:13][CH:2]=[C:3]3[C:11]4[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=4)[NH:5][C:4]3=[O:12])=[CH:19][CH:18]=2)(=[O:21])=[O:22])[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 4426510phenyl 4-aminobenzenesulfonateHCID 1784187413-(hydroxymethylidene)-1H-indol-2-one

Product 1

HCID 178517094HCID 178517094, compoundYield 23%

Procedure

The title compound was prepared in 23% yield from 3-hydroxymethylene-1,3-dihydro-indol-2-one and phenyl 4-aminobenzenesulfonate according to Procedure J: 1H NMR (DMSO-d6): δ10.8 (d, 1H), 10.5 (s, 1H), 8.6 (d, 1H), 7.7 (d, 2H), 7.6 (m, 3H), 7.4 (m, 2H), 7.3 (m, 1H), 7.0 (m., 3H), 6.9 (t, 1H), 6.8 (d, 1H); APCI−MS m/z 391 (M−H)−.

Sources & evidence

ORD record
ord-1d28340ac6904f2e847547104823f0bc
Source dataset
uspto-grants-2002_04
Patent number
US06369086B1

Reaction notes

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