HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Aminophenyl)-N-methylmethanesulfonamide--hydrogen chloride (1/1) → N-methyl-1-[4-[[5-(1,3-oxazol-5-yl)-2-oxo-1H-indol-3-ylidene]methylamino]phenyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Aminophenyl)-N-methylmethanesulfonamide--hydrogen chloride (1/1) | HCID 14234262 | — |
| Reactant | Ethoxymethylene-5-oxazol-5-yl-1,3-dihydro-indol-2-one | HCID 53832760 | — |
| Product | N-methyl-1-[4-[[5-(1,3-oxazol-5-yl)-2-oxo-1H-indol-3-ylidene]methylamino]phenyl]methanesulfonamide | HCID 178486286 | 56% |
Reaction Steps
The title compound was prepared in 56% yield from ethoxymethylene-5-oxazol-5-yl-1,3-dihydro-indol-2-one and N-methyl-4-aminophenylmethanesulfonamide hydrochloride according to Procedure J: 1H NMR (DMSO-d6): δ10.72 (d,1H), 10.67 (s, 1H), 8.71 (d, 1H), 8.37 (s, 1H), 7.43-7.34 (m, 7H), 6.89 (m, 2H), 4.28 (s, 2H), 2.54 (d, 3H); APCI−MS m/z 409 (MH)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06369086B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-a5986b6564e74075b0fb5a0f9bc03940 |
| Source note | uspto-grants-2002_04 |