8-[Ethoxymethylidene]-6H-[1,3]thiazolo[5,4-e]indol-7-one → HCID 178516997, compound

HRID 840898Notes

Reaction equation

HRID 840898 reaction equation
C(O[CH:4]=[C:5]1[C:16]2[C:8](=[CH:9][CH:10]=[C:11]3[C:15]=2[S:14][CH:13]=[N:12]3)[NH:7][C:6]1=[O:17])C.[NH2:18][C:19]1[CH:27]=[CH:26][C:22]2[NH:23][N:24]=[N:25][C:21]=2[CH:20]=1>>[N:23]1[C:22]2[CH:26]=[CH:27][C:19]([NH:18][CH:4]=[C:5]3[C:16]4[C:8](=[CH:9][CH:10]=[C:11]5[C:15]=4[S:14][CH:13]=[N:12]5)[NH:7][C:6]3=[O:17])=[CH:20][C:21]=2[NH:25][N:24]=1

Participants

3

Reactant 2

HCID 539908078-[Ethoxymethylidene]-6H-[1,3]thiazolo[5,4-e]indol-7-oneHCID 178507366HCID 178507366, compound

Product 1

HCID 178516997HCID 178516997, compoundYield 54%

Procedure

The title compound was prepared in 54% yield from 8-ethoxymethylene-6,8-dihydro-1-thia-3,6-diaza-as-indacen-7-one and 5-aminobenzotriazole according to Procedure J: 1H NMR (DMSO-d6): δ11.18 (d,1H), 10.9 (s, 1H), 9.23 (s, 1H), 8.12 (d, 1H), 7.96 (s, 1H), 7.78 (d, 1H), 7.48(s, 1H), 7.1 (d, 1H); APCI−MS m/z 333 (M−H)−.

Sources & evidence

ORD record
ord-74c4726d4ea7498482d2cd26fd661391
Source dataset
uspto-grants-2002_04
Patent number
US06369086B1

Reaction notes

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