4-Bromophenylhydrazine hydrochloride → HCID 178517005, compound

HRID 840918Notes

Reaction equation

HRID 840918 reaction equation
[S:1]1[C:12]2[C:4](=[CH:5][CH:6]=[C:7]3[C:11]=2[C:10](=O)[C:9](=[O:14])[NH:8]3)[N:3]=[CH:2]1.Cl.[Br:16][C:17]1[CH:22]=[CH:21][C:20]([NH:23][NH2:24])=[CH:19][CH:18]=1>>[Br:16][C:17]1[CH:22]=[CH:21][C:20]([NH:23]/[N:24]=[C:10]2\[C:9](=[O:14])[NH:8][C:7]3[C:11]\2=[C:12]2[S:1][CH:2]=[N:3][C:4]2=[CH:5][CH:6]=3)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 121574-Bromophenylhydrazine hydrochlorideHCID 117457566H-thiazolo[5,4-e]indole-7,8-dione

Product 1

HCID 178517005HCID 178517005, compoundYield 62%

Procedure

Prepared according to Example 96 with 6H-1-thia-3,6-diaza-as-indacen-7,8-dione (Procedure A) and 4-bromophenylhydrazine hydrochloride in 62% yield. 1H NMR (DMSO-d6): δ7.16 (d, J=8.5 Hz, 1H); 7.50 and 7.62 (Abq, J=8.8 Hz, 4H); 8.02 (d, J=8.5 Hz, 1H); 9.33 (s, 1H); 11.3 (s, 1H); 12.6 (s, 1H). ES−MS m/z 371, 373 (M−1)−.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b16bce2c05a34791b8835c1a5c0b59d0
Source dataset
uspto-grants-2002_04
Patent number
US06369086B1

Reaction notes

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