Hydrogen Peroxide → HCID 22620485, compound

Participants

Reaction Steps

Methyl 4-methylthio-6,7-dihydro-5H-benzocycloheptene-8-carboxylate (0.50 g, 2.01 mmol) was dissolved in methanol (10 ml), followed by adding thereto a 30% aqueous hydrogen peroxide solution (1.14 ml, 10.07 mmol) and sodium tungstate dihydrate (0.066 g, 0.201 mmol), and the resulting mixture was stirred at 70° C. for 5.5 hours. Water was added to the reaction mixture, followed by extraction with ethyl acetate (twice), and the extract solution was washed with water and a saturated aqueous sodium chloride solution and then dried over anhydrous magnesium sulfate. The solvent was distilled off under reduced pressure to obtain 0.589 g of methyl 4-methylsulfonyl-6,7-dihydro-5H-benzocycloheptene-8-carboxylate.

Provenance & Evidence