Water → HCID 135987425, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture of 37.9 g (0.100 mol) of 2,4-bis(2′,4′-dimethylphenyl)-6-(2′,4′-dihydroxyphenyl)-1,3,5-triazine, 14.5 g ( 0.105 mol) of potassium carbonate (Fluka, 99.0%) in 250 ml of N,N-dimethylformamide (DMF, Fluka, 99.5%) there are added dropwise with stirring at 80° C. 19.0 g (0.105 mol) of ethyl 2-bromopropionate (Fluka, 98%). The mixture is held at 80° C. for 1 h, then poured into 4 l of cold water and subjected to extraction with 2 l of ethyl acetate. The organic phase is filtered and washed with 2×500 ml of water and dried (MgSO4). Removal of the solvent and drying at 60° C./60 mmHg/24 h give 39.0 g of 2,4-bis(2′,4′-dimethylphenyl)-6-(2′-hydroxy-4′-(1″-(ethoxycarbonyl)ethoxy)phenyl)-1,3,5-triazine as pale yellow crystals of m.p. 120-122° C.

Provenance & Evidence