돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 84165생성일: 2026년 10월 25일

tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate → N-(2-(pyrrolidin-3-ylmethoxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

https://huagongshe.com/reaction/84165

반응식

참여 물질

역할이름HCID투입량
반응물tert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylateHCID 5237175—
반응물N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetateHCID 67607774—
생성물N-(2-(pyrrolidin-3-ylmethoxy)phenyl)pyridine-2-sulfonamide trifluoroacetateHCID 6760989439%

반응 단계

Intermediate 6b (solid) is prepared using tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate instead of tert-butyl 4-hydroxypiperidine-1-carboxylate using the procedure described for 6a (yield: 39% over the 4 steps).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08846930B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-85a26538ca064fc29b14f3603b7befd8
출처 메모uspto-grants-2014_09