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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 84168Generated: October 25, 2026

6-Chloro-2-(piperazin-1-yl)-1,3-benzoxazole → N-(4-(4-(6-chlorobenzo[d]oxazol-2-yl)piperazine-1-carbonyl)phenyl)pyridine-2-sulfonamide

https://huagongshe.com/reaction/84168

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2-(piperazin-1-yl)-1,3-benzoxazoleHCID 25219078—
Reactant4-(Pyridine-2-sulfonylamino)benzoic acidHCID 69409462—
ProductN-(4-(4-(6-chlorobenzo[d]oxazol-2-yl)piperazine-1-carbonyl)phenyl)pyridine-2-sulfonamideHCID 67609541—

Reaction Steps

Compound 14 is prepared using synthesis method 2 using intermediates 3b and 5c (yield: 56%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846930B2
Source datasetuspto-grants-2014_09
ORD IDord-fca130b3a5884313b0e8fcdff6816a8e
Source noteuspto-grants-2014_09