Ethinylestradiol → Norgestimate and Ethinyl Estradiol

Beteiligte Stoffe

Reaktionsschritte

PEG 8000 is micronized by Jet mill together with ethinyl estradiol at the ratio of ethinyl estradiol to PEG from 1:1 to 1:60. Adjust Jet mill to produce particle size of 5-10 μm. Norgestimate is micronized separately to particle size of 5-15 μm. Micronized norgestimate powder is electrically charged, and deposited on the substrate surface. Micronized PEG 8000/ethinyl estradiol mixture is triboelectrically charged, and deposited on top of norgestimate.

Herkunft & Nachweise