2,4-Dimethoxyphenyl isocyanate → HCID 73986455, compound

HRID 841902Notes

Reaction equation

HRID 841902 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[N:11]=[C:12]=[O:13].[NH2:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[N:20]([CH2:24][C:25]1[CH:30]=[CH:29][C:28]([Cl:31])=[C:27]([Cl:32])[CH:26]=1)[CH:19]=[C:18]2[CH:33]=[C:34]1[S:38][C:37](=[O:39])[NH:36][C:35]1=[O:40]>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[NH:11][C:12](=[O:13])[NH:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[N:20]([CH2:24][C:25]1[CH:30]=[CH:29][C:28]([Cl:31])=[C:27]([Cl:32])[CH:26]=1)[CH:19]=[C:18]2[CH:33]=[C:34]1[S:38][C:37](=[O:39])[NH:36][C:35]1=[O:40]

Participants

3

Reactant 2

HCID 6016372,4-Dimethoxyphenyl isocyanateHCID 73986453HCID 73986453, compound

Product 1

HCID 73986455HCID 73986455, compound

Procedure

The title compound was prepared by General Procedure 7 with 2,4-dimethoxyphenyl isocyanate and the amino compound from Example 47 as reactants. Nmr and ms data were consistent; ms m/e 598 (M+1). HPLC (System 1): purity greater than 80%.

Sources & evidence

ORD record
ord-09646c0fba69425183b1f60eaa7442c0
Source dataset
uspto-grants-2002_04
Patent number
US06372742B1

Reaction notes

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