Benzoyl chloride → HCID 73986460, compound

HRID 841903Notes

Reaction equation

[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[N:16]([CH2:20][C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([Cl:28])[CH:22]=1)[CH:15]=[C:14]2[CH:29]=[C:30]1[S:34][C:33](=[O:35])[NH:32][C:31]1=[O:36]>>[C:1]([NH:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[N:16]([CH2:20][C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([Cl:28])[CH:22]=1)[CH:15]=[C:14]2[CH:29]=[C:30]1[S:34][C:33](=[O:35])[NH:32][C:31]1=[O:36])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 73986453HCID 73986453, compound

Product 1

HCID 73986460HCID 73986460, compound

Procedure

The title compound was prepared by General Procedure 7 with benzoyl chloride and the amino compound from Example 47 as reactants. Nmr and ms data were consistent; ms m/e 523 (M+1). HPLC (System 1): purity greater than 80%.

Sources & evidence

ORD record: ord-6b12dfebf40d4d37aeeb044e4bd7e505
Source dataset: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06372742B1

Reaction notes

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